Search results for "Disease classification"

showing 7 items of 7 documents

A kernel support vector machine based technique for Crohn’s disease classification in human patients

2017

In this paper a new technique for classification of patients affected by Crohn’s disease (CD) is proposed. The proposed technique is based on a Kernel Support Vector Machine (KSVM) and it adopts a Stratified K-Fold Cross-Validation strategy to enhance the KSVM classifier reliability. Traditional manual classification methods require radiological expertise and they usually are very time-consuming. Accordingly to three expert radiologists, a dataset composed of 300 patients has been selected for KSVM training and validation. Each patient was codified by 22 extracted qualitative features and classified as Positive or Negative as the related histological specimen result showed the CD. The eff…

Computer sciencebusiness.industryKernel support vector machineHuman patientK-fold cross-validation020206 networking & telecommunicationsPattern recognition02 engineering and technologyPredictive value030218 nuclear medicine & medical imagingSupport vector machine03 medical and health sciences0302 clinical medicine0202 electrical engineering electronic engineering information engineeringClassification methodsCrohn disease classificationArtificial intelligencebusinessClassifier (UML)
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Evaluation of a Support Vector Machine Based Method for Crohn’s Disease Classification

2019

Crohn’s disease (CD) is a chronic, disabling inflammatory bowel disease that affects millions of people worldwide. CD diagnosis is a challenging issue that involves a combination of radiological, endoscopic, histological, and laboratory investigations. Medical imaging plays an important role in the clinical evaluation of CD. Enterography magnetic resonance imaging (E-MRI) has been proven to be a useful diagnostic tool for disease activity assessment. However, the manual classification process by expert radiologists is time-consuming and expensive. This paper proposes the evaluation of an automatic Support Vector Machine (SVM) based supervised learning method for CD classification. A real E-…

Crohn's diseasemedicine.diagnostic_testComputer sciencebusiness.industryFeature vectorFeature extractionSupervised learningMagnetic resonance imagingPattern recognitionmedicine.diseaseCrohn’s disease classification Feature extraction Feature reduction K-fold cross-validation Supervised learning Support vector machinesSupport vector machinemedicineMedical imagingArtificial intelligencebusinessReliability (statistics)
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Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study

2018

Purpose: To evaluate patients with resolved versus confirmed ARDS, identify subgroups with substantial mortality risk, and to determine the utility of day 2 ARDS reclassification. Methods: Our primary objective, in this secondary LUNG SAFE analysis, was to compare outcome in patients with resolved versus confirmed ARDS after 24 h. Secondary objectives included identifying factors associated with ARDS persistence and mortality, and the utility of day 2 ARDS reclassification. Results: Of 2377 patients fulfilling the ARDS definition on the first day of ARDS (day 1) and receiving invasive mechanical ventilation, 503 (24%) no longer fulfilled the ARDS definition the next day, 52% of whom initial…

MaleARDSmedicine.medical_treatmentlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]ARDS reassessment; ARDS Survival; Berlin criteria ARDS; Persisting ARDS;Critical Care and Intensive Care Medicineassisted ventilation0302 clinical medicineRisk Factors030212 general & internal medicinerisk factor AdultTidal volumecomparative studyeducation.field_of_studyRespiratory Distress SyndromeMortality rateRemission Inductiontidal volumeARDS reassessment; ARDS Survival; Berlin criteria ARDS; Persisting ARDS; Critical Care and Intensive Care MedicineARDS reassessmentartificial ventilationclinical trialimmunosuppressive treatmentadult respiratory distress syndromeMiddle AgedARDS SurvivalMonte Carlo methodmedicine.anatomical_structureclassificationpositive end expiratory pressureCardiologyDisease ProgressionSOFA scoredisease severityFemaleAdultmedicine.medical_specialtyPopulationdisease classificationArticleNO03 medical and health sciencesremissionlength of stayAnesthesiologyInternal medicinemedicinepneumoniaSequential Organ Failure Assessment ScoreHumanshumaneducationAgedMechanical ventilationhospital mortalityLungbusiness.industryRisk Factordisease associationRespiratory Distress Syndrome AdultPersisting ARDSmedicine.diseasemajor clinical studymortalityRespiration Artificialbreathing rate030228 respiratory systemdisease exacerbationBerlin criteria ARDSbusinessIntensive care medicine
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Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study

2016

Rationale: Noninvasive ventilation (NIV) is increasingly used in patients with acute respiratory distress syndrome (ARDS). The evidence supporting NIV use in patients with ARDS remains relatively sparse.Objectives: To determine whether, during NIV, the categorization of ARDS severity based on the PaO2/FiO2 Berlin criteria is useful.Methods: The LUNG SAFE (Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure) study described the management of patients with ARDS. This substudy examines the current practice of NIV use in ARDS, the utility of the PaO2/FiO2 ratio in classifying patients receiving NIV, and the impact of NIV on outcome.Measurements and Main…

MaleARDSprocedureblood oxygen tensionCritical Care and Intensive Care MedicineSeverity of Illness Indexlaw.invention0302 clinical medicinelawHospital MortalityRespiratory Distress SyndromeAcute respiratory distress syndromeadult respiratory distress syndromeMiddle AgedIntensive care unitIntensive Care Unitsmedicine.anatomical_structureTreatment Outcomepriority journalpositive end expiratory pressureNoninvasive ventilationdisease severityFemaletreatment outcome AgedNoninvasive ventilationprospective studyHumanAdultPulmonary and Respiratory Medicinemedicine.medical_specialtycohort analysiIntensive Care Unitdisease classificationAcute respiratory distressArticleNO03 medical and health sciencesacute respiratory distress syndrome; noninvasive ventilationlength of staySeverity of illnessSettore MED/41 - ANESTESIOLOGIAmedicineSequential Organ Failure Assessment ScoreHumansIn patientAcute respiratory distress syndrome; Noninvasive ventilation; Aged; Female; Hospital Mortality; Humans; Intensive Care Units; Male; Middle Aged; Respiratory Distress Syndrome Adult; Severity of Illness Index; Treatment Outcome; Noninvasive Ventilation; Pulmonary and Respiratory Medicine; Critical Care and Intensive Care MedicineIntensive care medicineoutcome assessmentAgedLungbusiness.industryRespiratory Distress Syndrome Adult030208 emergency & critical care medicinemedicine.diseasemajor clinical studymortalityrespiratory tract diseasesbreathing ratemulticenter study030228 respiratory systemincidenceObservational studyobservational studybusinessAcute respiratory distress syndrome; Noninvasive ventilation;
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Determinants of self-reported smoking and misclassification during pregnancy, and analysis of optimal cut-off points for urinary cotinine: a cross-se…

2013

10 p. Objectives: To estimate the prevalence and factors associated with smoking and misclassification in pregnant women from INMA (INfancia y Medio Ambiente, Environment and Childhood) project, Spain, and to assess the optimal cut-offs for urinary cotinine (UC) that best distinguish daily and occasional smokers with varying levels of second-hand smoke (SHS) exposure.-- Design: We used logistic regression models to study the relationship between sociodemographic variables and self-reported smoking and misclassification (self-reported non-smokers with UC >50 ng/ml). Receiver operating characteristic (ROC) curves were used to calculate the optimal cut-off point for discriminating smokers. The…

PediatricsCross-sectional studyEpidemiologyurinalysisLogistic regressionToxicologychemistry.chemical_compoundEpidemiology1506accuracyObstetricsadultarticleGeneral Medicinefemalematernal smokingbiomarkerwomenPublic Health1716medicine.medical_specialtyUrinary systemprevalencedisease classificationself reportsmokerssmokingmedicine1724controlled studycotininehumanSmoking and TobaccoPregnancypassive smokingReceiver operating characteristicMEDICINEbusiness.industryResearchinterviewmedicine.diseasemajor clinical studythird trimester pregnancy1692pregnant womancessationchemistrysensitivity and specificityexposure1734Cut-offPreventive MedicinebusinessCotinine
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A Classification Proposal for Peri-Implant Mucositis and Peri-Implantitis: A Critical Update

2015

Definitions of peri-implant mucositis and peri-implantitis vary in the literature, and no clear criteria have been established for the diagnosis and treatment of such disorders. This study proposes a classification for peri-implant mucositis and peri-implantitis based on the severity of the disease, using a combination of peri-implant clinical and radiological parameters to classify severity into several stages (Stage 0A and 0B = peri-implant mucositis, and Stage I to IV = periimplantitis). Following a review of the literature on the subject and justification of the proposed peri-implant disease classification, the latter aims to facilitate professional communication and data collection for…

Peri-implantitisdiseasePeri-implant mucositisdental implantbusiness.industryDentistryDisease classificationOdontologíaDiseasemedicine.diseaseClassificationperi-implant mucositisArticleCommunity healthMucositismedicineperi-implant.Stage (cooking)businessGeneral Dentistryperi-implantitis
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Randomized Controlled Clinical Trials in Mild-Moderate Ulcerative Colitis

2012

The Authors review and critically discuss the most recent published evidence on treatment of mild-moderate ulcerative colitis both in the induction and maintenance of remission. Evidence on each drug is introduced by the related statement of ECCO guidelines. A brief introduction on disease classification and the need of standardizing indexes of clinical and endoscopic activity is also provided. Concluding remarks stress the heterogeneity of available studies both in the selection of patients and the outcomes evaluated and suggest the development of an international consensus in setting standards which will allow studies' results to be compared and combined to produce high quality clinical r…

medicine.medical_specialtyPathologyAlternative medicineMEDLINEAdministration OralSeverity of Illness IndexRemission inductionAdministration RectalAdrenal Cortex HormonesSeverity of illnessHumansMedicineColitisIntensive care medicineRandomized Controlled Trials as TopicPharmacologybusiness.industryRemission InductionDisease classificationGeneral Medicinemedicine.diseaseUlcerative colitisSalicylatesClinical trialColitis UlcerativebusinessAlgorithmsReviews on Recent Clinical Trials
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